H.O.S.E (aka S.H.O.E) is a term used for playing a mixed game of poker consisting of four different poker games. H stands for Hold'em, O for Omaha Eight or Better, S for 7 Card Stud and E for 7 Card Stud Eight or Better. This form of poker is most common at higher limit casino tables and is popular since it requires players to be skilled at many different forms of poker to succeed.

H.O.R.S.E. is a similar variant that has Razz thrown into the mix. Razz is 7 Card Stud played for low.

Until recently tournaments in H.O.S.E (last time 2003) and H.O.R.S.E (last time 2004) was featured at the World Series of Poker but in 2005 no such tournament was hosted, disappointing many players. The H.O.R.S.E tournament will be reinstated at the 2006 World Series of Poker event with a record $50,000 buy-in to participate.